Philipp Tschandl

This study benchmarks H&E-based gene expression prediction methods in skin tissue, finding poor performance overall and limited utility for single-cell analysis.

The paper constructs a scRNA-seq atlas of chronic inflammatory skin diseases by integrating datasets from 27 diseases, identifying shared and disease-specific inflammatory signatures.

This study identifies stiffness-dependent LOX regulation via HIF-1 in psoriasis, linking ECM modifications to disease progression through mechanosensitive fibroblasts.