Jie Du

This study identifies UBA1 as a protective factor against myocardial ischemia/reperfusion injury by reducing endoplasmic reticulum-mitochondria contacts through Pdzd8 ubiquitination.

This study identifies 12-HETE as a key metabolite in thoracic aortic dissection (TAD) that activates BLT2 receptors on macrophages, driving inflammation and VSMC phenotype switching, and shows that targeting this pathway can reduce TAD progression.

This study identifies novel somatic mutations and altered mutation frequencies in Chinese colorectal cancer patients using whole exome sequencing, highlighting differences from TCGA data.