Author

Kate E. Lawlor

Hudson Institute of Medical ResearchORCID 0000-0003-0471-6842Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Alexander Thomas ElfordiD· 1 shared André L. SamsoniD· 1 shared Andrew MetziD· 1 shared Anne Cao Le· 1 shared Annette V. JacobseniD· 1 shared Arthur Richard KitchingiD· 1 shared Asha JoisiD· 1 shared Ashley L. WeiriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

Alexander Thomas ElfordORCID

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2 papers

Recent·Most cited

Cell BiologySciencePeer-reviewedAug 27, 2026

A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease

Jiyi Pang, Aysha Al‐Ani, Komal M. Patel…·James M. Murphy

This study identifies dysregulated epithelial cell death signaling in inflammatory bowel disease, showing it persists during remission despite therapy.

10 citationstop 1%

humanexperimental assay

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ImmunologyJCI InsightPeer-reviewedJul 8, 2025

Treatment of anti-myeloperoxidase glomerulonephritis using recombinant deoxyribonuclease I is enhanced by adeno-associated virus gene therapy

Anne Cao Le, Virginie Oudin, Jonathan Dick…·Kim Maree O’Sullivan

This study shows that DNase I treatment reduces ecDNA-driven inflammation in MPO-ANCA GN, and gene therapy enhances its therapeutic effect by extending its half-life.

3 citations

mousebulk RNA-seq

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