Arthur Richard Kitching

The paper identifies a novel HLA-DR15-restricted CD4 T cell epitope from PR3 associated with vasculitis and describes its unconventional presentation mechanism.

The paper identifies rare RELA variants in autoimmune diseases and shows they affect NF-κB and IFNβ transcriptional activity and immune cell subsets.

This study shows that DNase I treatment reduces ecDNA-driven inflammation in MPO-ANCA GN, and gene therapy enhances its therapeutic effect by extending its half-life.