Author

Alison Layton

University of YorkORCID 0000-0003-0473-3319Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetic & Genomic Medicine· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Aamir Butt· 1 shared Alex V. Anstey· 1 shared Alexander J. Hogg· 1 shared Alexandra Bonsall· 1 shared Alison Godwin· 1 shared André FrankeiD· 1 shared André ReisiD· 1 shared Anne C BartoniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenetic & Genomic Medicine

Aamir Butt

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2 papers

Recent·Most cited

Genetic & Genomic MedicineGenome MedicinePeer-reviewedDec 17, 2025

Genetic liability to psoriasis predicts severe disease outcomes

Jake R. Saklatvala, Samuel Lessard, Maris Teder‐Laving…·Kathy Sands

This study identifies genetic risk factors associated with severe psoriasis and shows that polygenic risk scores can predict severe disease outcomes better than traditional risk factors.

DOI 10.1186/s13073-025-01561-2

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 20, 2025

Non-canonical inflammasome drives intrinsic anti-microbial responses in human Natural Killer (NK) cells.

Nathan Georges François Leborgne, Jadie Acklam, Alexander J. Hogg…·Dave Boucher

This study identifies a non-canonical inflammasome in human NK cells that mediates anti-microbial responses against Salmonella without canonical inflammasome components.

DOI 10.1101/2025.10.20.682800

humanproteomics

𝕏 PostBluesky