Author

Nicolas N. Nassar

Cincinnati Children's Hospital Medical CenterORCID 0000-0003-0481-4784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Assay:CUT&Tag· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

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Alexander William ThormaniD· 1 shared Andrew B. HerriD· 1 shared Ardythe Luxion MorrowiD· 1 shared Behrouz ShamsaeiiD· 1 shared David A. HildemaniD· 1 shared James K. ReigleiD· 1 shared Jarek MelleriD· 1 shared Juechen YangiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperBioinformatics

Alexander William ThormanORCID

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1 paper

Recent·Most cited

BioinformaticsScience AdvancesPeer-reviewedAug 30, 2024

Accelerating Drug Discovery and Repurposingby Combining Transcriptional Signature Connectivity with Docking

Alexander William Thorman, James K. Reigle, Somchai Chutipongtanate…·Jarek Meller

This paper introduces ceSAR, a method combining docking and transcriptional signature connectivity to improve drug discovery and repurposing by reducing false positives and computational costs.

16 citations

CUT&Tagdeep learning

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