Author
University of CincinnatiORCID 0000-0002-0672-5382Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Jackson Spieser, Juechen Yang, Jarek Meller, Krushna Patra, Behrouz Shamsaei
GPCR-Nexus integrates structured databases and literature using a multi-agent AI system to provide accurate, traceable knowledge about GPCRs.
bioRxiv · Apr 14, 2026 · PreprintBioinformatics
Alexander William Thorman, James K. Reigle, Somchai Chutipongtanate, Juechen Yang, Behrouz Shamsaei, Marcin Pilarczyk, Mehdi Fazel‐Najafabadi, Rafał Adamczak, Michal Kouril, Surbhi Bhatnagar, Sarah A. Hummel, Wen Niu, Ardythe Luxion Morrow, Maria Czyzyk-Krzeska, Robert Erne McCullumsmith, , Jarek Meller
This paper introduces ceSAR, a method combining docking and transcriptional signature connectivity to improve drug discovery and repurposing by reducing false positives and computational costs.
Science Advances · Aug 30, 2024Peer-reviewedBioinformatics
Marcin Pilarczyk, Mehdi Fazel‐Najafabadi, Michal Kouril, Behrouz Shamsaei, Juozas Vasiliauskas, Wen Niu, Naim Al Mahi, Lixia Zhang, Nicholas A. Clark, Yan Ren, Shana White, Rashid Saadman Karim, Huan Xu, Jacek Biesiada, Mark F. Bennett, , Mario Medvedovic
iLINCS provides a web-based platform for analyzing omics signatures of diseases and cellular perturbations through integrative analytics and visualization tools.
Nature Communications · Aug 9, 2022Peer-reviewedBioinformatics
Marouen Ben Guebila, Camila M. Lopes‐Ramos, Deborah A. Weighill, Abhijeet R. Sonawane, Rebekka Burkholz, Behrouz Shamsaei, John Platig, Kimberly Glass, Marieke L. Kuijjer, John F Quackenbush
GRAND is a database of gene regulatory network models across human conditions, enabling comparison between biological states and drug response prediction.
Nucleic Acids Research · Sep 8, 2021Peer-reviewedGenomics
Behrouz Shamsaei, Szymon Chojnacki, Marcin Pilarczyk, Mehdi Fazel Najafabadi, Wen Niu, Chuming Chen, Karen E. ROSS, Andrea D. Matlock, Jeremy L. Muhlich, Somchai Chutipongtanate, Jie Zheng, John Turner, Dušica Vidović, Jacob D. Jaffe, Michael J. MacCoss, , Jarek Meller
piNET is a web platform for analyzing and visualizing proteomics data, including PTMs, by connecting them to biological knowledge and LINCS signatures.
Nucleic Acids Research · May 27, 2020Peer-reviewedBioinformatics
Adam J. Funk, Guillaume Labilloy, James K. Reigle, Rawan S. Alnafisah, Michael R. Heaven, Rosalinda C. Roberts, Behrouz Shamsaei, Kenneth D. Greis, Jarek Meller, Robert Erne McCullumsmith
This study identifies region-specific PSD-95 interactomes in human brain regions and links them to potential drug targets using bioinformatics and perturbagen databases.
bioRxiv · May 4, 2020 · PreprintNeuroscience