Author

Joshua D. Manduca

University of GuelphORCID 0000-0003-0483-5286Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Organism:rat· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1 Approach:statistical model· 1

Frequent Co-Authors

Melissa L. PerreaultiD· 3 shared Madeleine Coppolino· 2 shared Olivia O. F. WilliamsiD· 2 shared Paula T Henry-DuruiD· 2 shared Cecilia B. Micelli· 1 shared Colby J. PerriniD· 1 shared Eric SoubeyrandiD· 1 shared Jasmin LalondeiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersNeuroscience

Melissa L. PerreaultORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 14, 2025

Cannflavin B ameliorates social and anxiety deficits and neuronal systems dysfunction in adolescent rats exposed to prenatal valproic acid

Olivia O. F. Williams, Madeleine Coppolino, Joshua D. Manduca…·Melissa L. Perreault

This study shows cannflavin B reduces social and anxiety deficits and neuronal dysfunction in VPA-exposed rats.

DOI 10.1101/2025.09.14.676092

ratexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 3, 2024

Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats

Olivia O. F. Williams, Madeleine Coppolino, Cecilia B. Micelli…·Melissa L. Perreault

This study examines sex-specific effects of prenatal valproic acid exposure on neuronal structure and function in rat cortical and hippocampal neurons, revealing differences in activity, morphology, and gene expression.

DOI 10.1101/2024.09.03.611039

ratexperimental assay

𝕏 PostBluesky

NeurosciencebioRxivPreprintJul 30, 2019

Sex differences in innate and adaptive neural oscillatory patterns predict resilience and susceptibility to chronic stress in rats

Rachel-Karson Thériault, Joshua D. Manduca, Melissa L. Perreault

The paper identifies sex-specific neural oscillatory patterns in rats under chronic stress that predict resilience or susceptibility to depression-like behaviors.

4 citations

ratelectronic health records

𝕏 PostBluesky