Melissa L. Perreault

Cannflavin B ameliorates social and anxiety deficits and neuronal systems dysfunction in adolescent rats exposed to prenatal valproic acid

This study shows cannflavin B reduces social and anxiety deficits and neuronal dysfunction in VPA-exposed rats.

Prenatal exposure to valproic acid induces sex-specific alterations in cortical and hippocampal neuronal structure and function in rats

This study examines sex-specific effects of prenatal valproic acid exposure on neuronal structure and function in rat cortical and hippocampal neurons, revealing differences in activity, morphology, and gene expression.

Human Cerebral Spheroids Undergo Activity Dependent Changes In Cellular Composition And MicroRNA Expression

The paper shows that increasing neuronal activity in human cerebral spheroids increases new neurons and decreases new glial cells, with reduced miR-135a expression.

Cannabis Vapour Exposure Alters Neural Circuit Oscillatory Activity In A Neurodevelopmental Model Of Schizophrenia: Exploring The Differential Impact Of Cannabis Constituents

This study examines how cannabis vapour with THC or balanced THC:CBD affects oscillatory activity in a schizophrenia model, finding THC suppresses activity while CBD balances its effects.

Sex differences in innate and adaptive neural oscillatory patterns predict resilience and susceptibility to chronic stress in rats

The paper identifies sex-specific neural oscillatory patterns in rats under chronic stress that predict resilience or susceptibility to depression-like behaviors.