Author

Alexandra M. Thornock

Boston Children's HospitalORCID 0000-0003-0511-4376Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:database / resource· 1 Approach:experimental assay· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alexandra PanoviD· 1 shared Arvene Golbazi· 1 shared Brandon M. GassawayiD· 1 shared David P. NusinowiD· 1 shared David Timothy BishopiD· 1 shared Devin K. SchweppeiD· 1 shared Edward L. HuttliniD· 1 shared Eila Maenpaa· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperSystems Biology

Alexandra PanovORCID

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2 papers

Recent·Most cited

GeneticsbioRxivPreprintFeb 9, 2026

Functional characterization of the 9q34.13 locus identifies RAPGEF1 as modulating risk for melanoma and nevi via RAS activation

Rohit Thakur, Mai Xu, Alexandra M. Thornock…·Kevin M. Brown

This study identifies RAPGEF1 as a gene modulating melanoma and nevi risk through RAS activation, using fine-mapping, expression data, and functional assays.

DOI 10.64898/2025.12.03.691936

humanwhole-genome sequencing

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Systems BiologyCellPeer-reviewedMay 1, 2021

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, José Navarrete-Perea…·Steven P. Gygi

The paper creates two large-scale cell-line-specific human interactomes using affinity-purification mass spectrometry and identifies shared and cell-specific protein interactions.

960 citationstop 1%

humanproteomics

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