Cell BiologybioRxivPreprint
Single Nucleus Multiome Analysis Reveals Early Inflammatory Response to High-Fat Diet in Mouse Pancreatic Islets
Isabell Victoria Strandby Ernst, Lasse Lehtonen, Sille Marie Nilsson…·Jesper Grud Skat Madsen
The paper uses single nucleus multiomics to study early inflammatory responses in mouse pancreatic islets under high-fat diet, finding proinflammatory gene activation and reduced beta-cell identity.