Molecular BiologyCell MetabolismPeer-reviewed
NRF2 activation induces NADH-reductive stress providing a metabolic vulnerability in lung cancer
Tommy Weiss‐Sadan, Maolin Ge, Makiko Hayashi…·Liron Bar‐Peled
The paper shows NRF2 activation in KEAP1 wildtype lung cancers causes NADH-reductive stress, making them vulnerable to Complex I inhibition.
158 citationstop 1%