Author
Massachusetts General HospitalORCID 0000-0001-7823-4374Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Charles H. Adelmann, Xiaoqing Liu, Allison E. Greuel…·David E. Fisher
The paper shows that CRTC, not phosphorylated CREB1, drives cAMP-induced transcription across multiple cell types, challenging the canonical model of CREB1 activation.
Corey Nathaniel Cunningham, Alex J. Bott, Charles H. Adelmann…·Jared P. Rutter
This study identifies SLC16A6 as the melanosomal tyrosine transporter, showing it is essential for melanosome biogenesis and function.
Charles H. Adelmann, Avanthika Venkatachalam, Lingjuan Huang…·David E. Fisher
This study shows that MFSD12 is essential for mouse embryonic development by supplying reduced cysteine to lysosomes, and cysteamine treatment rescues Mfsd12 knockout mice.
Tommy Weiss‐Sadan, Maolin Ge, Makiko Hayashi…·Liron Bar‐Peled
The paper shows NRF2 activation in KEAP1 wildtype lung cancers causes NADH-reductive stress, making them vulnerable to Complex I inhibition.