Author

Daniel A. Martin-Alarcon

Massachusetts Institute of TechnologyORCID 0000-0003-0547-8129Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:protein sequence· 1

Frequent Co-Authors

Alexander D. Wissner‐GrossiD· 1 shared Amirul Muhammad Islam· 1 shared Dat P. TruongiD· 1 shared Demian Park· 1 shared Dmitrij RappoportiD· 1 shared Edward S. BoydeniD· 1 shared Giovanni Talei Franzesi· 1 shared Himashi P. AndaraarachchiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBioengineering

Alexander D. Wissner‐GrossORCID

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2 papers

Recent·Most cited

BiochemistryProceedings of the National Academy of SciencesPeer-reviewedMar 17, 2026

Dual-encoder contrastive learning accelerates enzyme discovery

Jason W. Rocks, Dat P. Truong, Dmitrij Rappoport…·Joshua E. Goldford

This paper introduces Horizyn-1, a deep learning framework for enzyme discovery that improves performance with larger datasets and validates its effectiveness through experimental testing.

8 citationstop 1%

protein sequencedeep learning

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BioengineeringbioRxivPreprintSep 5, 2024

In Vivo Optical Clearing of Mammalian Brain

Giovanni Talei Franzesi, Ishan Gupta, Ming Hu…·Edward S. Boyden

This study shows that modifying the optical properties of a mammalian brain can enhance deep imaging without affecting native physiology.

9 citations

mouseimaging

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