Ming Hu

This paper introduces VADER1, a red GEVI that enables reliable in vivo two-photon voltage imaging with millisecond resolution and supports dual-color imaging with calcium indicators.

This study characterizes the oral microbiome across 9,431 participants and identifies associations with metabolic health, finding specific microbial features linked to metabolic traits and disease classification.

The paper develops two new genetically encoded voltage indicators (JEDI3sub and JEDI3hyp) for improved two-photon recording of subthreshold voltage dynamics in vivo.

The paper introduces FORCE1s, a GEVI that enables robust two-photon voltage imaging in awake mice with high signal-to-noise and reliable spike detection.

The paper identifies molecular logic underlying cellular specializations in the cochlear nuclear complex using single-nucleus RNA sequencing and Patch-seq.

The paper examines cortical acetylcholine dynamics during behavioral state transitions, finding that axon activity and behavior predict ACh levels.

This study shows that modifying the optical properties of a mammalian brain can enhance deep imaging without affecting native physiology.

The paper investigates the local circuit organization of noradrenergic neurons in the locus coeruleus of adult mice, revealing diverse morpho-electric types and chain-like electrical coupling patterns.

This paper introduces a non-toxic rabies virus system for long-term in vivo imaging of neuronal networks, showing minimal toxicity and normal visual response properties over 10 weeks.

The paper examines population coding in V1 and V4 of macaques during a visual task, finding that in V4, informative neurons show stronger synchrony and correlations within coding pools than across them.

The paper predicts upcoming behavioral choices from spiking activity in monkey V1 by analyzing the overlap between stimulus and choice information in population vectors.

The paper introduces a model to read-out neural spike trains for stimulus discrimination, showing it outperforms population PSTH in classification and reveals functional subnetworks in V1 and V4.

The paper uses three-photon microscopy to correlate structural and functional features in visual cortical areas of awake mice.

The paper identifies an inhibitory circuit between somatostatin and parvalbumin interneurons that modulates the reliability of pyramidal neuron responses to visual stimuli, improving stimulus discrimination.