MicrobiologybioRxivPreprint
MX2 Mediates Collapse of the HIV-1 Capsid
Andrew Goodale, Szu‐Wei Huang, Nathalia Almeida…·Michael H. Malim
This study identifies the minimal MX2 region required for HIV-1 restriction and shows that MX2 binding disrupts the capsid lattice, leading to premature fragmentation and preventing viral nuclear import.