Cu Duy Nguyen

The paper establishes reference samples with high-coverage whole-genome sequencing to create truth sets for somatic mutation and germline variant detection using NGS technologies.

This study evaluates reproducibility and accuracy of cancer mutation detection using whole-genome and whole-exome sequencing across multiple sequencing centers and bioinformatics pipelines.

This study evaluates somatic CNV callers using NGS data from 91 samples with varying factors, finding that caller choice and tumor purity significantly impact call quality.