Author

Nikhil Sharma

Max Planck Institute for Evolutionary BiologyORCID 0000-0003-0598-016XUnclaimed ORCID profile · follow to get notified of new preprints

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Nikhil Sharma4 papers · Cleveland Clinic

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Evolutionary Biology· 2

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Approach:statistical model· 2

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Arne TraulseniD· 2 shared Joachim KrugiD· 2 shared Suman G. DasiD· 2 shared

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2025-2025 · peak 2/yr

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Arne TraulsenORCID

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2 papers

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Evolutionary BiologybioRxivPreprintSep 4, 2025

Population structure amplifies mutation load

Nikhil Sharma, Suman G. Das, Arne Traulsen, Joachim Krug

The paper shows that spatial structure amplifies mutation load, reducing the effectiveness of natural selection and promoting the proliferation of less-fit types in structured populations.

1 citation

statistical model

𝕏 PostBluesky

Evolutionary BiologyNature CommunicationsPeer-reviewedMar 10, 2025

Graph-structured populations elucidate the role of deleterious mutations in long-term evolution

Nikhil Sharma, Suman G. Das, Joachim Krug, Arne Traulsen

The paper investigates how spatial structure affects evolutionary outcomes by identifying amplifier and suppressor graphs for mutant fixation and their impact on long-term fitness.

5 citations

statistical model

𝕏 PostBluesky