Author

Nikhil Sharma

Cleveland Clinic

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Ajay H. ZalavadiaiD· 1 shared Allison Foreman· 1 shared Alokkumar JhaiD· 1 shared Amy C BurrowsiD· 1 shared Apoorva L. MylavarapuiD· 1 shared Bence RácziD· 1 shared Cornelia C. BergmanniD· 1 shared Daniel H. GeschwindiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperNeuroscience

Ajay H. ZalavadiaORCID

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3 papers

Recent·Most cited

CardioWAS Pathway-Based RNA-Seq and Genome Integration Platform for CVD Omics-Wide Associations

Yuvraj Singh, Nikhil Sharma, Kabir Raghuvanshi, Jennifer M. Kwan, Alokkumar Jha

CARDIOWAS integrates RNA-seq and GWAS data to identify disease-specific pathways in cardiovascular diseases, enabling pathway-level analysis and variant-pathway associations.

bioRxiv · Oct 6, 2025 · PreprintBioinformatics

Ifit2 regulates murine-coronavirus spread to the spinal cord white matter and its associated myelin pathology

Madhav D. Sharma, Debanjana Chakravarty, Ajay H. Zalavadia, Amy C Burrows, Patricia A. Rayman, Nikhil Sharma, Lawrence C. Kenyon, Cornelia C. Bergmann, Ganes C. Sen, Jayasri Das Sarma

This study shows that Ifit2 deficiency in mice leads to severe viral spread and demyelination in the spinal cord during chronic RSA59 infection.

bioRxiv · Jun 6, 2022 · PreprintNeuroscience

Reduced prefrontal synaptic connectivity and disturbed oscillatory population dynamics in the CNTNAP2 model of autism

María T. Lázaro, Jiannis Taxidis, Tristan Shuman, Iris Bachmutsky, Taruna Ikrar, Rommel Andrew Santos, G. Mark Marcello, Apoorva L. Mylavarapu, Swasty Chandra, Allison Foreman, Rachna Goli, Duy Tran, Nikhil Sharma, Michelle Azhdam, Hongmei Dong, , Peyman Golshani

This study investigates the effects of CNTNAP2 loss-of-function mutations in mice, finding reduced synaptic connectivity and altered oscillatory dynamics in the prefrontal cortex associated with autism-like behaviors.

Cell Reports · May 1, 2019Peer-reviewedNeuroscience