Suman G. Das

The paper investigates how intra- and extracellular β-lactamase activity contributes to collective β-lactam survival in E. coli under cefotaxime stress.

The paper shows that spatial structure amplifies mutation load, reducing the effectiveness of natural selection and promoting the proliferation of less-fit types in structured populations.

The paper models compensatory evolution in a fitness landscape with adaptational tradeoffs, showing that resistance mutations can be replaced by lower-cost variants without losing resistance.

The paper investigates how spatial structure affects evolutionary outcomes by identifying amplifier and suppressor graphs for mutant fixation and their impact on long-term fitness.

SAM is a MATLAB-based tool for segmenting and analyzing mother machine data to detect and correct imaging aberrations in rod-shaped bacteria.