Naoto Kubota

This study shows that PTBP1 depletion in astrocytes causes unique splicing changes without neuronal features, suggesting PTBP1 alone is insufficient for neuronal reprogramming.

Shiba and scShiba systematically identify differential RNA splicing across RNA-seq platforms with high accuracy and low false positives, even with small sample sizes.

The paper introduces a method to identify promoter usage QTL (puQTL) using RNA-seq data, revealing novel variant-gene associations and linking them to complex traits.

The paper identifies functional variants in hematopoietic transcription factor footprints associated with immune system disease risk using integrated GWAS and QTL datasets.