Author

David Nikom

University of California, RiversideORCID 0000-0003-2722-6002Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Ayden Arient· 1 shared Min ZhangiD· 1 shared Naoto KubotaiD· 1 shared Sika ZhengiD· 1 shared

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2025-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperNeuroscience

Ayden Arient

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1 paper

Recent·Most cited

NeuroscienceeLifePeer-reviewedNov 21, 2025

PTBP1 Depletion in Mature Astrocytes Reveals Distinct Splicing Alterations Without Neuronal Features

Min Zhang, Naoto Kubota, David Nikom…·Sika Zheng

This study shows that PTBP1 depletion in astrocytes causes unique splicing changes without neuronal features, suggesting PTBP1 alone is insufficient for neuronal reprogramming.

DOI 10.7554/elife.107683

mousebulk RNA-seq

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