NeuroscienceScientific ReportsPeer-reviewed
Novel Small Molecules Targeting the Intrinsically Disordered Structural Ensemble of α-Synuclein Protect Against Diverse α-Synuclein Mediated Dysfunctions
Gergely Tóth, Thomas Neumann, Amandine Berthet…·Lisa McConlogue
This study identifies small molecules that target the intrinsically disordered ensemble of α-synuclein, showing they can inhibit misfolding, restore phagocytosis, and block cellular transmission of α-synuclein.
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