Author

Baixue Yang

The Wistar InstituteORCID 0009-0008-0333-5144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:genetic perturbation / CRISPR· 3 Organism:human· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Aidan R. ColeiD· 3 shared Amandine AmalriciD· 3 shared Apoorva UbovejaiD· 3 shared Evan LevasseuriD· 3 shared Jeff Danielson· 3 shared Katherine M. AirdiD· 3 shared Nadine HempeliD· 3 shared Nathaniel W. SnyderiD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

Aidan R. ColeORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Cancer BiologyNature AgingPeer-reviewedJul 30, 2026

The chemotherapy-induced senescence-associated secretome promotes cell detachment and metastatic dissemination through metabolic reprogramming

Aidan R. Cole, Raquel Buj, Apoorva Uboveja…·Katherine M. Aird

This study shows that chemotherapy-induced senescence-associated secretome promotes metastasis in ovarian cancer by reprogramming metabolism and increasing cell detachment.

6 citationstop 3%

humanbulk RNA-seq

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Cancer BiologyNaturePeer-reviewedMay 27, 2026

αKG-mediated carnitine synthesis promotes homologous recombination via histone acetylation

Apoorva Uboveja, Baixue Yang, Raquel Buj…·Katherine M. Aird

This study shows that αKG-mediated carnitine synthesis supports HR proficiency by promoting histone acetylation, which enhances DNA repair.

10 citations

humanproteomics

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Cancer BiologybioRxivPreprintFeb 8, 2025

Zinc availability in the tumor microenvironment dictates anti-PD1 response in CDKN2ALow tumors via increased macrophage phagocytosis

Raquel Buj, Aidan R. Cole, Jeff Danielson…·Katherine M. Aird

This study shows that zinc availability in the tumor microenvironment affects anti-PD1 therapy response in CDKN2A-low tumors through macrophage phagocytosis.

3 citations

mouseproteomics

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