Author

Scott H. Chandler

University of California, Los AngelesORCID 0000-0003-0638-0246Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3

Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1

Frequent Co-Authors

Sharmila VenugopaliD· 3 shared Antonios PantazisiD· 2 shared Martina Wiedau‐PazosiD· 2 shared Riccardo OlceseiD· 2 shared Soju SekiiD· 2 shared David H. TermaniD· 1 shared Dwayne D. SimmonsiD· 1 shared Igor SpigelmaniD· 1 shared

Activity by Year

2019-2021 · peak 2/yr

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10 top collaborators · 34 mutual co-author links

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3 shared papersNeuroscience

Sharmila VenugopalORCID

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3 papers

Recent·Most cited

NeurosciencebioRxivPreprintDec 16, 2021

Diminished GAD67 Terminals and Ambient GABA Inhibition Associated with Reduced Motor Neuron Recruitment Threshold in the SOD1G93A ALS mouse

Sharmila Venugopal, Zohal Ghulam-Jelani, Dwayne D. Simmons, Scott H. Chandler

The paper examines age-dependent changes in inhibitory terminals and GABA inhibition in SOD1G93A ALS mouse motor neurons, finding reduced GAD67 terminals and ambient GABA inhibition in vulnerable motor pools.

1 citation

mouseexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedSep 17, 2019

Circuit-Specific Early Impairment of Proprioceptive Sensory Neurons in the SOD1G93A Mouse Model for ALS

Soju Seki, Toru Yamamoto, Kiara N. Quinn…·Sharmila Venugopal

The paper identifies early proprioceptive sensory neuron impairments in SOD1G93A mice, showing Nav1.6 channel deficits and reflexive defects in ALS.

37 citations

mouseelectronic health records

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NeurosciencePLoS Computational BiologyPeer-reviewedJun 21, 2019

Resurgent Na+ Current Offers Noise Modulation in Bursting Neurons

Sharmila Venugopal, Soju Seki, David H. Terman…·Scott H. Chandler

This study shows that resurgent Na+ current stabilizes burst discharge and noise tolerance in neurons through membrane resonance and feedback mechanisms.

13 citations

electronic health recordsstatistical model

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