Petr Pecina

Sequestration of the polyunsaturated fatty acids protects the cells with oxidative phosphorylation deficiency from ferroptosis

The paper identifies that OXPHOS-deficient cells sequester polyunsaturated fatty acids into triacylglycerols to protect against ferroptosis, observed in patient fibroblasts and hypoxia conditions.

Recurrent Single-Nucleotide Insertions in the Mitochondrial Second Light-Strand Promoter Cause Tubulointerstitial Kidney Disease

The paper identifies recurrent mtDNA variants, particularly in the LSP2 promoter, as a cause of tubulointerstitial kidney disease in families with maternal inheritance.

COX6B1 secures a redox-sensitive step in early cytochrome c oxidase assembly

The paper investigates the role of COX6B1 in cytochrome c oxidase assembly, finding it essential for both early redox-sensitive steps and late stabilization of the complex.

Bioenergetics of human spermatozoa in patients with testicular germ cell tumour

This study examines the bioenergetic patterns of cryopreserved sperm from testicular germ cell tumor patients compared to normozoospermic samples using XF Analyzer and 2P-FLIM, revealing cryopreservation-induced metabolic impairments.