Genetic & Genomic MedicinemedRxivPreprint
Large-scale genome- and phenome-wide analyses reveal the genetic architecture, pathophysiology and comorbidity of restless legs syndrome
Xiaoxi Jing, Zi Wang, Jacob Williams…·Yajie Zhao
This study identifies 15 novel RLS-associated loci and links them to neurodevelopmental programs, while revealing over 100 comorbidities and brain structural associations through genome- and phenome-wide analyses.
DOI 10.64898/2026.05.21.26353752