Author
Stanford MedicineORCID 0000-0003-0665-8797Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Debra Van Egeren, Ryan O. Schenck, Aziz Khan…·Christina N. Curtis
This study shows that many premalignant colorectal polyps contain multiple genetic lineages, indicating polyclonal origins rather than single-cell expansion.
Tuhin Kumar Guha, Edward D. Esplin, Aaron M. Horning…·Michael P. Snyder
The paper uses spatial CODEX experiments to show early colorectal cancer microenvironment changes in FAP, including CAFs, immune suppression, and beta-catenin nuclear translocation.
Yizhou Zhu, Hayan Lee, Shannon M. White…·Michael P. Snyder
This study shows that early colorectal cancer loses promoter-enhancer connectivity, leading to gene expression changes and a two-phase model of transcriptional regulation.
Alison Figueroa Almeda, Susan M. Grimes, HoJoon Lee…·Hanlee P. Ji
The paper describes the development of a gastric cancer registry integrating clinical and genomic data to support translational research.
Winston R. Becker, Stephanie A. Nevins, Derek C. Chen…·William James Greenleaf
The paper uses single-cell data to show a continuum of cell state and composition changes from polyps to colorectal cancer, identifying stem-like cells and regulatory markers.