Author

Marcello Chang

University of PennsylvaniaORCID 0000-0003-0687-0683Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Arjun RajiD· 2 shared Alex J. HughesiD· 1 shared Christopher J. CoteiD· 1 shared Ian A. MellisiD· 1 shared Ilya LukoniniD· 1 shared Jasmine LeeiD· 1 shared Jennifer M. KalishiD· 1 shared Jihwan ParkiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersSystems Biology

Arjun RajORCID

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2 papers

Recent·Most cited

Systems BiologyCell SystemsPeer-reviewedJun 14, 2022

Systematically quantifying morphological features reveals constraints on organoid phenotypes

Lauren E. Beck, Jasmine Lee, Christopher J. Cote…·Arjun Raj

The paper quantifies morphological features of organoids under perturbations to identify constraints on their phenotypes, finding scaling relationships and parameter caps that vary with age and culture conditions.

22 citations

imagingstatistical model

𝕏 PostBluesky

GeneticsPLoS GeneticsPeer-reviewedJan 9, 2019

Allele-specific RNA imaging shows that allelic imbalances can arise in tissues through transcriptional bursting

Orsolya Symmons, Marcello Chang, Ian A. Mellis…·Arjun Raj

The paper uses allele-specific RNA imaging to show that allelic imbalances in tissues can result from transcriptional bursting and low mRNA abundance.

34 citations

mousebulk RNA-seq

𝕏 PostBluesky