Lauren E. Beck

Systematically quantifying morphological features reveals constraints on organoid phenotypes

The paper quantifies morphological features of organoids under perturbations to identify constraints on their phenotypes, finding scaling relationships and parameter caps that vary with age and culture conditions.

Responsiveness to perturbations is a hallmark of transcription factors that maintain cell identity

The paper identifies transcription factors that maintain cell identity by analyzing their responsiveness to perturbations in human iPSC-derived cardiac myocytes and fibroblasts.

Quantius: Generic, high-fidelity human annotation of scientific images at 105-clicks-per-hour

Quantius provides a crowd-based image annotation platform that achieves high-fidelity human annotation at 105 clicks per hour, matching deep learning performance while reducing time and cost.