Jonas Muhr

This study shows SOX21 suppresses glioblastoma stem cells by repressing AP-1 activity, leading to reduced tumor growth and improved survival in mouse models.

This paper shows that HIF2α reduces MYCN protein levels and promotes a low-risk noradrenergic phenotype in neuroblastoma, suggesting HIF2 has tumor suppressor rather than oncogenic function.

The paper shows that chromatin accessibility is essential for enhancer activity in different cell types, as it correlates more with neighboring gene expression than transcription factor binding.