Author

Thomas Filleron

Institut universitaire du cancer de Toulouse OncopoleORCID 0000-0003-0724-0659Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Bastien CabarrouiD· 2 shared Julien MazièresiD· 2 shared Agnese CristiniiD· 1 shared Alejandra MartíneziD· 1 shared Amélie LusqueiD· 1 shared Amy J. HeidersbachiD· 1 shared Anna SalvioniiD· 1 shared Anne Casanova· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Bastien CabarrouORCID

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3 papers

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedSep 23, 2026

Persistent TOP1 cleavage complexes in drug-tolerant cells drive adaptive resistance to EGFR-targeted therapies in lung cancer

Mathéa Géraud, Rémi Gence, Anne Casanova…·Olivier Sordet

The paper shows that persistent TOP1 cleavage complexes in drug-tolerant lung cancer cells drive adaptive resistance to EGFR-targeted therapies by promoting mutagenesis and reveals TDP1 loss as a targetable vulnerability.

DOI 10.1126/sciadv.aeh9099

humanexperimental assay

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Cancer BiologybioRxivPreprintMar 12, 2026

Systemic neoantigen-specific T cells reveal central determinants of PD-(L)1 blockade efficacy

Célia Ramade, Noémie Thébault, Clara‐Maria Scarlata…·Maha Ayyoub

The paper identifies coordinated neoantigen-specific CD8 T cell responses as key predictors of PD-(L)1 therapy efficacy in non-small cell lung cancer patients.

DOI 10.64898/2026.03.10.710196

humanbulk RNA-seq

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GeneticsbioRxivPreprintDec 9, 2024

Next generation sequencing identifies a pattern of novel germline variants in early-onset colorectal cancer

Pierre Vande Perre, Ayman Al Saati, Bastien Cabarrou…·Christine Toulas

The paper identifies 15 genes with high-impact germline variants overrepresented in early-onset colorectal cancer (EOCRC) and shows 11 of these variants are specific to EOCRC.

DOI 10.1101/2024.12.09.627474

humanwhole-exome sequencing

𝕏 PostBluesky