Author

Rémi Gence

Centre National de la Recherche ScientifiqueORCID 0000-0003-0747-3540Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1

Frequent Co-Authors

Agnese CristiniiD· 1 shared Alba Diz-MuñoziD· 1 shared Amélie LusqueiD· 1 shared Anne Casanova· 1 shared Anne PradinesiD· 1 shared Arnaud MétaisiD· 1 shared Brigitte Raynaud‐MessinaiD· 1 shared Camille Taha· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Agnese CristiniORCID

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2 papers

Recent·Most cited

Molecular BiologyScience AdvancesPeer-reviewedSep 23, 2026

Persistent TOP1 cleavage complexes in drug-tolerant cells drive adaptive resistance to EGFR-targeted therapies in lung cancer

Mathéa Géraud, Rémi Gence, Anne Casanova…·Olivier Sordet

The paper shows that persistent TOP1 cleavage complexes in drug-tolerant lung cancer cells drive adaptive resistance to EGFR-targeted therapies by promoting mutagenesis and reveals TDP1 loss as a targetable vulnerability.

DOI 10.1126/sciadv.aeh9099

humanexperimental assay

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Cell BiologyThe Journal of Cell BiologyPeer-reviewedAug 20, 2025

Moesin controls cell-cell fusion and osteoclast function

Ophélie Dufrançais, Marianna Plozza, Marie Juzans…·Christel Vérollet

This study identifies moesin's role in osteoclast fusion and function, showing its impact on bone resorption and disease therapy.

11 citations

mousehuman

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