MicrobiologybioRxivPreprint
Mapping the journey of a neuro-invasive virus in zebrafish larvae: contrasted viral spread and type I interferon responses in periphery and central nervous system
Valerio Laghi, Laurent Boucontet, Hannah Wiggett…·Jean‐Pierre Levraud
This study tracks SINV spread in zebrafish larvae, showing CNS entry via neurons, persistent CNS infection, and differential IFN responses, with a mathematical model revealing IFN's dual role in infection control.