Author

Margo Aertgeerts

Universitair Ziekenhuis LeuvenORCID 0000-0003-0734-380XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Heidi SegersiD· 2 shared Jan CoolsiD· 2 shared Alexandra Bacquelaine VelosoiD· 1 shared Alexandra PančíkováiD· 1 shared Daan DierickxiD· 1 shared Félicien Renard· 1 shared Ilan Bischops· 1 shared Jente M. Schoenaker· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersGenomics

Heidi SegersORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 8, 2025

Long-read single-cell genome, transcriptome and open chromatin profiling links genotype to phenotypes.

Alexandra Pančíková, Ruben Cools, Marios Eftychiou…·Jonas Demeulemeester

SPLONGGET enables comprehensive genotype-phenotype analysis by integrating long-read single-cell genome, transcriptome, and open chromatin profiling in thousands of cells.

2 citations

humanscRNA-seq

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Cancer BiologybioRxivPreprintMar 3, 2024

Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis

Alexandra Bacquelaine Veloso, Thomas Slegers, Jente M. Schoenaker…·Marlies Vanden Bempt

This study shows that targeting EZH2 and HDACs together induces ferroptosis in hematological malignancies by upregulating cholesterol biosynthesis and causing metabolic stress.

DOI 10.1101/2024.03.03.583195

humanbulk RNA-seq

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