Author

Thomas Slegers

Universitair Ziekenhuis LeuvenORCID 0000-0002-1346-6577Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Alexandra Bacquelaine VelosoiD· 1 shared Daan DierickxiD· 1 shared Félicien Renard· 1 shared Heidi SegersiD· 1 shared Ilan Bischops· 1 shared Jan CoolsiD· 1 shared Jente M. Schoenaker· 1 shared Kris JacobsiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alexandra Bacquelaine VelosoORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintMar 3, 2024

Dual targeting of EZH2 and Histone Deacetylases in hematological malignancies promotes transcriptional and metabolic deregulation leading to ferroptosis

Alexandra Bacquelaine Veloso, Thomas Slegers, Jente M. Schoenaker…·Marlies Vanden Bempt

This study shows that targeting EZH2 and HDACs together induces ferroptosis in hematological malignancies by upregulating cholesterol biosynthesis and causing metabolic stress.

DOI 10.1101/2024.03.03.583195

humanbulk RNA-seq

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