Author

Laura Childers

Duke UniversityORCID 0000-0003-0761-2256Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:zebrafish· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Jieun ParkiD· 2 shared Michel BagnatiD· 2 shared Siyao WangiD· 2 shared Fernando MartineziD· 1 shared John Franklin RawlsiD· 1 shared Richard Liu· 1 shared Robert J. BarryiD· 1 shared Stephen A. Watts· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 24 mutual co-author links

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2 shared papersDevelopmental Biology

Jieun ParkORCID

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2 papers

Recent·Most cited

Genome wide transcriptional changes underlie gradual and recurrent adaptation to protein malnutrition in zebrafish

Siyao Wang, Laura Childers, Fernando Martinez, Michel Bagnat, Jieun Park

This study shows that zebrafish adapt to protein malnutrition through genome-wide transcriptional changes that enhance intestinal function and survival.

PLoS Genetics · Sep 28, 2026Peer-reviewedDevelopmental Biology

Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

Laura Childers, Jieun Park, Siyao Wang, Richard Liu, Robert J. Barry, Stephen A. Watts, John Franklin Rawls, Michel Bagnat

This study shows that zebrafish gut microbiome influences protein absorption by altering lysosome-rich enterocytes' expression of digestion machinery and microbial interactions.

eLife · Oct 30, 2024Peer-reviewedCell Biology