John Franklin Rawls

The External Microbiome Communicates with the Developing Zebrafish (Danio rerio) Embryo Through the Chorion and Influences Developmental Trajectory

This study shows the external microbiome influences zebrafish embryonic development through the chorion, affecting transcriptomics, proteomics, and physiological processes.

Intestinal enteroendocrine cell subtype differentiation and hormone production in zebrafish

The paper identifies EEC subtypes and hormone production in zebrafish using single-cell RNA sequencing and mass spectrometry, revealing distinct precursor relationships.

Protein absorption in the zebrafish gut is regulated by interactions between lysosome rich enterocytes and the microbiome

This study shows that zebrafish gut microbiome influences protein absorption by altering lysosome-rich enterocytes' expression of digestion machinery and microbial interactions.

Transcriptional integration of distinct microbial and nutritional signals by the small intestinal epithelium

This study investigates how the small intestinal epithelium integrates microbial and nutritional signals through transcriptional responses in mice, revealing distinct and overlapping regulatory mechanisms.

High fat diet induces microbiota-dependent silencing of enteroendocrine cells

This study shows high fat diet causes EEC silencing, a nutrient-insensitive state linked to ER stress, which is microbiota-dependent in zebrafish.

Hnf4a mediates microbial control of intestinal gene expression and inflammation

This study identifies Hnf4a as a mediator of microbial control of intestinal gene expression and inflammation across species.