Author

Philippa Harding

Guy's HospitalORCID 0000-0003-0763-3516Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alexander J. SmithiD· 1 shared Dulce Lima CunhaiD· 1 shared Hajrah Sarkar· 1 shared Huiqing ZhouiD· 1 shared Jonathan EintrachtiD· 1 shared Maja WojtynskaiD· 1 shared Mariya MoosajeeiD· 1 shared Rachael A. PearsoniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 16 mutual co-author links

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1 shared paperDevelopmental Biology

Alexander J. SmithORCID

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2 papers

Recent·Most cited

Developmental BiologyStem Cell ReportsPeer-reviewedSep 25, 2025

Human macula formation involves two waves of retinoic acid suppression via CYP26A1 that modulate cell cycle exit and cone subtype specification

Philippa Harding, Maja Wojtynska, Alexander J. Smith…·Rachael A. Pearson

This study examines CYP26A1's role in human macula development, showing two RA suppression waves that affect cell cycle exit and cone subtype specification.

6 citations

humanbulk RNA-seq

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GeneticsMolecular Therapy — Nucleic AcidsPeer-reviewedJun 26, 2023

Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs

Dulce Lima Cunha, Hajrah Sarkar, Jonathan Eintracht…·Mariya Moosajee

This study uses patient iPSC-derived models to test TRIDs for restoring PAX6 function in aniridia, identifying amlexanox as effective in increasing PAX6 levels and rescuing disease phenotypes.

14 citations

humanexperimental assay

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