Author

Hajrah Sarkar

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Mariya MoosajeeiD· 2 shared Cécile MéjécaseiD· 1 shared Dulce Lima CunhaiD· 1 shared Huiqing ZhouiD· 1 shared Jonathan EintrachtiD· 1 shared Lyes ToualbiiD· 1 shared Neelima Nair· 1 shared Nicholas OweniD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPathology

Mariya MoosajeeORCID

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2 papers

Recent·Most cited

Dominant RDH12-retinitis pigmentosa impairs photoreceptor development and cone function in retinal organoids

Cécile Méjécase, Ya Zhou, Nicholas Owen, Pablo Soro-Barrio, Riccardo Cheloni, Neelima Nair, Hajrah Sarkar, Lyes Toualbi, Mariya Moosajee

This study generates a retinal organoid model of dominant RDH12-retinitis pigmentosa, showing impaired photoreceptor development and cone function.

Frontiers in Cell and Developmental Biology · Apr 29, 2025Peer-reviewedPathology

Restoration of functional PAX6 in aniridia patient iPSC-derived ocular tissue models using repurposed nonsense suppression drugs

Dulce Lima Cunha, Hajrah Sarkar, Jonathan Eintracht, Philippa Harding, Huiqing Zhou, Mariya Moosajee

This study uses patient iPSC-derived models to test TRIDs for restoring PAX6 function in aniridia, identifying amlexanox as effective in increasing PAX6 levels and rescuing disease phenotypes.

Molecular Therapy — Nucleic Acids · Jun 26, 2023Peer-reviewedGenetics