Jan Hinrichsen

This study links neuronal cell loss and gliosis in hippocampal sclerosis to tissue stiffness using mechanical testing and deep learning analysis of histopathology.

This paper develops a method to estimate patient-specific brain mechanical properties from DTI data, showing that voxel-resolved stiffness distributions improve simulation accuracy compared to region-based approaches.

This study shows fractional anisotropy from MRI correlates with brain tissue stiffness, suggesting it can be used as a non-invasive marker for mechanical properties.