Arnd Doerfler

The Mechanical Fingerprint of Hippocampal Sclerosis Linking Neuronal Cell Loss and Gliosis to Tissue Stiffness

This study links neuronal cell loss and gliosis in hippocampal sclerosis to tissue stiffness using mechanical testing and deep learning analysis of histopathology.

Towards patient-specific biomechanical human brain models

This paper develops a method to estimate patient-specific brain mechanical properties from DTI data, showing that voxel-resolved stiffness distributions improve simulation accuracy compared to region-based approaches.

Fractional Anisotropy as a Surrogate Marker of Brain Mechanics

This study shows fractional anisotropy from MRI correlates with brain tissue stiffness, suggesting it can be used as a non-invasive marker for mechanical properties.

Spatiotemporal Patterns Differentiate Hippocampal Sharp-Wave Ripples from Interictal Epileptiform Discharges in Mice and Humans

This study identifies spatiotemporal patterns distinguishing hippocampal sharp-wave ripples from interictal epileptiform discharges in mice and humans, introducing a detection tool for improved analysis.