Author

Yimei Li

Princeton UniversityORCID 0000-0003-0774-4515Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:Bayesian inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Aartjan J.W. te VelthuisiD· 2 shared Bjarke Frost NielseniD· 2 shared Bryan Thomas GrenfelliD· 2 shared Alan S. PerelsoniD· 1 shared Carla Lourens· 1 shared Simon A. LeviniD· 1 shared Simon LeviniD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

Aartjan J.W. te VelthuisORCID

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 31, 2026

Defective Viral Genomes Reveal History-dependent Self-regulation of Type I Interferon Dynamics

Yimei Li, Carla Lourens, Bjarke Frost Nielsen…·Aartjan J.W. te Velthuis

The paper develops a Bayesian model to show that defective viral genomes modulate type I interferon dynamics by both inducing and suppressing IFN through cumulative exposure, explaining how pandemic viruses evade innate immunity.

DOI 10.64898/2026.10.30.763053

Bayesian inference

𝕏 PostBluesky

Systems BiologyPLoS Computational BiologyPeer-reviewedApr 22, 2026

Spatio-temporal modelling of in vitro viral infection: the impact of defective interfering particles on type I interferon response

Yimei Li, Bjarke Frost Nielsen, Simon A. Levin…·Bryan Thomas Grenfell

The paper develops a spatially explicit model of in vitro viral infection with DIPs, showing how they affect IFN response and plaque morphology.

1 citation

statistical model

𝕏 PostBluesky