Nicole E. Franks

This study shows GAS1 is essential for kidney development through both Hedgehog-dependent and -independent mechanisms, with Gas1 deletion causing renal agenesis in mice.

This study maps the expression of Hedgehog signaling components in mouse taste papillae during postnatal development and adult homeostasis, revealing distinct patterns in different regions and stages.

This study identifies KIF17 as a dual regulator of Hedgehog signaling in cerebellar development, with opposing roles in Purkinje cells and granule neuron progenitors.

This study identifies Plexins as novel components of the Hedgehog pathway, showing they promote signaling through their GAP activity and primary cilia interaction.