Benjamin L. Allen

This study shows GAS1 is essential for kidney development through both Hedgehog-dependent and -independent mechanisms, with Gas1 deletion causing renal agenesis in mice.

This study shows KIF3C is essential for cerebellar development through regulating Bergmann glia density and patterning, independent of Hedgehog signaling.

This study maps the expression of Hedgehog signaling components in mouse taste papillae during postnatal development and adult homeostasis, revealing distinct patterns in different regions and stages.

This study shows that Semaphorin receptors antagonize Wnt signaling by promoting beta-catenin degradation, independent of primary cilia.

This study identifies KIF17 as a dual regulator of Hedgehog signaling in cerebellar development, with opposing roles in Purkinje cells and granule neuron progenitors.

This study identifies Plexins as novel components of the Hedgehog pathway, showing they promote signaling through their GAP activity and primary cilia interaction.

This study identifies dual, tissue-specific roles for the Hedgehog co-receptor BOC in promoting and antagonizing HH signaling during craniofacial development.

This paper describes a portable short course designed to engage underrepresented undergraduate students in developmental biology, showing improved understanding and awareness of scientific careers.

The paper investigates epigenomic and transcriptomic changes in Danforth’s short tail mice, finding minimal chromatin changes but coordinated dysregulation of hedgehog signaling.