Author

Luca Madaro

Istituto PasteurORCID 0000-0003-0839-5724Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Chiara D’ErcoleiD· 2 shared Laura VirtaneniD· 2 shared Lorenzo GiordaniiD· 2 shared Veronica RuggieriiD· 2 shared Alberto MaconeiD· 1 shared Alessandra RenziniiD· 1 shared Alessio D’AlessioiD· 1 shared Annunziata D’EliaiD· 1 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

Chiara D’ErcoleORCID

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintApr 10, 2026

Reelin engages non-canonical signaling pathways to drive endothelial remodeling and plasticity

Dante Maria Stea, Sofia Nutarelli, Maria Teresa Viscomi…·Alessio D’Alessio

This study identifies Reelin as a regulator of endothelial plasticity through non-canonical FAK- and AKT-dependent pathways, promoting vascular remodeling without full mesenchymal transition.

DOI 10.64898/2026.04.08.717341

humanproteomics

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NeuroscienceMilitary Medical ResearchPeer-reviewedJan 1, 2026

A Translational Preclinical Strategy for Chronic Spinal Cord Injury: Neuroprotective and Regenerative Potential of Botulinum Neurotoxin Type A combined with Muscle Atrophy Prevention via Electrostimulation

Valentina Mastrorilli, Siro Luvisetto, Veronica Ruggieri…·Sara Marinelli

This study shows that combining botulinum neurotoxin type A with electrical muscle stimulation improves motor function and reduces neuropathic pain in chronic spinal cord injury.

DOI 10.1016/j.mmr.2026.100049

mouseexperimental assay

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Cell BiologybioRxivPreprintDec 3, 2025

Spatial and Multiomic profiling of muscle regeneration dynamics in Duchenne Muscular Dystrophy

Laura Virtanen, Chiara D’Ercole, Lucile Saillard…·Lorenzo Giordani

This study identifies NOTCH3 and GLIS3 as contributors to regeneration impairment in Duchenne Muscular Dystrophy using spatial transcriptomics and multiomic profiling.

DOI 10.64898/2025.12.02.691824

mousehuman

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Molecular BiologyCell ReportsPeer-reviewedDec 1, 2022

Spatially resolved transcriptomics reveals innervation-responsive functional clusters in skeletal muscle

Chiara D’Ercole, Paolo D’Angelo, Veronica Ruggieri…·Luca Madaro

The paper uses spatially resolved transcriptomics to identify innervation-responsive functional clusters in skeletal muscle and shows changes in atrophic signaling and polyamine metabolism upon denervation.

48 citations

mousespatial transcriptomics

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