Author

Alessandro Barenghi

European Molecular Biology LaboratoryORCID 0000-0003-0840-6358Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Molecular Biology· 2 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Organism:E. coli· 1 Organism:human· 1 Research Focus:protein design· 1

Frequent Co-Authors

James A. SawitzkeiD· 2 shared Adriana Castillo Caballero· 1 shared Alexander Websdale· 1 shared Balint DoleschalliD· 1 shared Blanka Cerreti· 1 shared Chiara MorelliiD· 1 shared Donald L. Court· 1 shared Ellen HutchinsoniD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

James A. SawitzkeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Molecular BiologyPLoS ONEPeer-reviewedApr 3, 2026

Enhancement of RecET-mediated in vivo linear DNA assembly by a xonA mutation

James A. Sawitzke, Nina Costantino, Adriana Castillo Caballero…·Donald L. Court

The paper improves in vivo linear DNA assembly efficiency by deleting the xonA gene, which encodes Exonuclease I, enhancing both RecET and lambda Red systems.

DOI 10.1371/journal.pone.0344368

E. coliDNA methylation

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJan 12, 2026

Iterative engineering of a compact Cas9 ortholog for in vivo gene editing via single AAV delivery

Alessandro Barenghi, Jamie A. Hackett, Neil E. Humphreys, James A. Sawitzke

The paper engineers a compact Cas9 ortholog, enCme2, for efficient in vivo gene editing via single AAV delivery, showing high specificity and minimal off-target activity.

DOI 10.64898/2026.01.12.698990

mousehuman

𝕏 PostBluesky

NeurosciencebioRxivPreprintJan 17, 2020

Identification of a novel population of peripheral sensory neuron that regulates blood pressure

Chiara Morelli, Laura Castaldi, Sam J. Brown…·Paul A. Heppenstall

The paper identifies a novel population of sensory neurons that regulate blood pressure through the autonomic nervous system.

DOI 10.1101/2020.01.17.909960

mouseexperimental assay

𝕏 PostBluesky