Xin Li

The paper proposes a two-route model for SARS-CoV-2 RTC function in jumping transcription, identifies a motif for METTL3 recognition, and reports TRS hairpins for NSP15 cleavage and RNA methylation.

The paper identifies recombination regions and mutation sites in SARS-CoV-2, SARS-CoV, and SARS-like CoVs, linking specific genetic features to pandemic emergence.

The paper proposes a negative feedback model explaining SARS-CoV-2 replication and transcription regulation through nsp15 cleavage of transcription regulatory sequences.