Zhi Cheng

How the replication and transcription complex functions in jumping transcription of SARS-CoV-2

The paper proposes a two-route model for SARS-CoV-2 RTC function in jumping transcription, identifies a motif for METTL3 recognition, and reports TRS hairpins for NSP15 cleavage and RNA methylation.

A negative feedback model to explain regulation of SARS-CoV-2 replication and transcription

The paper proposes a negative feedback model explaining SARS-CoV-2 replication and transcription regulation through nsp15 cleavage of transcription regulatory sequences.

Precise annotation of human, chimpanzee, rhesus macaque and mouse mitochondrial genomes using 5’ and 3’ end small RNAs

The paper annotates mitochondrial genomes of human, chimpanzee, rhesus macaque, and mouse using 5' and 3' end small RNAs at 1 base-pair resolution, revealing novel functions and conserved sequence blocks.

Two novel lncRNAs discovered in human mitochondrial DNA using PacBio full-length transcriptome data

The paper uses PacBio full-length transcriptome data to discover two novel lncRNAs in human mitochondrial DNA and propose a new class of lncRNAs called ltiRNAs.