Siddhartha S. Jana

The paper investigates the effect of the D155Y mutation in SARS-CoV-2 ORF3a protein on its interaction with caveolin-1, showing weakened binding affinity.

The paper analyzes mutations in the ORF3a gene of Indian SARS-CoV2 genomes, finding single and double point mutations that may affect virulence and suggesting therapeutic implications.

The paper compares SARS-CoV2 genomes from India and China to analyze spatial and molecular arrangements, revealing potential differences in viral origins and evolution.

The paper investigates codon alteration patterns in two neurodegenerative diseases using numerical representation and classification, finding strong class codons are most mutated and mutations in the first or second positions are more deleterious.

The paper investigates NBC-2, a naproxen bio-conjugate with amino alcohol, showing enhanced anti-inflammatory effects by inhibiting NF-κB signaling and reducing pro-inflammatory proteins in macrophages.